Download Atlas of Confocal Laser Scanning In-vivo Microscopy in by Prof.Dr. med. Rudolf F. Guthoff, Christophe Baudouin MD, PDF

By Prof.Dr. med. Rudolf F. Guthoff, Christophe Baudouin MD, Phd, Prof.Dr. rer. nat. Joachim Stave (auth.)

Confocal microscopy with laser scanning expertise yields in-vivo photos of ocular and ocular adnexal surfaces which are so very good that they rival histology by way of quality.This distinctive atlas and textbook demonstrates general in-vivo anatomy of the cornea, limbus and conjunctiva, quantifies a variety of mobile constructions utilizing cell-density calculations and establishes correlations among novel optical sections of assorted ailments of the ocular floor and medical findings. moreover, it helps the translation of novel high-magnification optical sections through evaluating corneal and conjunctival imprint cytology with in-vivo photos and describes early inflammatory adjustments in corneal grafts, in addition to corneal conjunctivalisation in limbal stem mobilephone deficiency, corneal dystrophies or infections, flap interface and margin features after laser in-situ keratomileusis (LASIK). furthermore, it instructs the reader approximately diagnostic and healing follow-up suggestions and offers a quick creation to purposes in different fields akin to dentistry and ear, nostril and throat surgery.

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Additional info for Atlas of Confocal Laser Scanning In-vivo Microscopy in Ophthalmology: Principles and Applications in Diagnostic and Therapeutic Ophthalmology

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LCs present as bright corpuscular particles with dendritic cell morphology and a diameter of up to 15 mm. LC distribution follows a gradient from low numbers in the center to higher cell densities in the periphery of the cornea. Moreover, confocal in vivo microscopy permits differentiation of LC bodies lacking dendrites, LCs with small dendritic processes forming a local network, and LCs forming a meshwork via long interdigitating dendrites (Fig. 8a–c). Whereas almost all the cells located in the periphery of the cornea demonstrate long processes interdigitating with the corneal epithelium, those in the center of the cornea often lack dendrites, most probably underlining their immature phenotype [26].

LC distribution follows a gradient from low numbers in the center to higher cell densities in the periphery of the cornea. Moreover, confocal in vivo microscopy permits differentiation of LC bodies lacking dendrites, LCs with small dendritic processes forming a local network, and LCs forming a meshwork via long interdigitating dendrites (Fig. 8a–c). Whereas almost all the cells located in the periphery of the cornea demonstrate long processes interdigitating with the corneal epithelium, those in the center of the cornea often lack dendrites, most probably underlining their immature phenotype [26].

B Confocal in-vivo microscopy image of abnormal corneal-conjunctival junction at the limbus. c Impression cytology of the limbus showing the same abnormal corneal–conjunctival junction 43 44 Chapter 5 Confocal Laser Scanning In Vivo Microscopy a b c d Fig. 22 Filamentous keratitis in a case of Sjögren’s syndrome. a Slit-lamp photograph of a 51-year-old woman showing severe filamentous keratitis. b Im- a Fig. 23 Keratoconjunctivitis sicca. a Corneal metaplasia before treatment: polymorphism, enlarged cells, and reflective nuclei.

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